A Chartered Accountant, she spent six years at Norwich Union (now Aviva) before becoming one of the founders of Virgin Direct in 1995. Three years later, she set up the Virgin One account, which was acquired by the Royal Bank of Scotland in 2001. She subsequently spent five years at RBS before returning to Virgin as CEO of Virgin Money.
In November 2016 she was appointed as the UK Government's Women in Finance Champion, and in July 2017 she became a founder member of its Business Diversity and Inclusion Group. In 2018 she was named Leader of the Year at the Lloyds Bank National Business Awards.
She is Chair of the Prince's Foundation and Trustee of the Tate. She sits on the UK Government's Industrial Strategy Council, Mayor of London's Business Advisory Board, CRUK Corporate Board, Financial Inclusion Policy Forum and Lloyds Culture Advisory Group.
She was made a Dame in the 2019 New Year's Honours list.